Usefulness of some primary anti-human antibodies in immunohistochemistry in guinea pig.

The commercially available antibodies for immunohistochemical purposes, though numerous and diversified, are mostly designed to detect human antigens. This study was undertaken to evaluate the usefulness of anti-human antigen antibodies in guinea pig tissues. The subjects of our interest were mostly skin and striated muscles and it was important for us to stain vascular and neural elements and to visualize separate cell kinds, including also skin Langerhans cells and the cells, contributing to inflammatory infiltrations.